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Know Your Bodybuilding Supplement - L-Tyrosine
L-tyrosine is a non-essential amino acid that plays a role in the creation of protein. The body can make it from the amino acid phenylalanine but nutritional sources include animal meats, wheat, oatmeal and seafood. It performs a multitude of important roles in the body including the alleviation of depression, enhancement of thyroid efficiency, strengthening of the immune system, prevention of neurological degeneration and protection of the skin. Bodybuilders find it useful for several reasons: 1. It offsets the stress and fatigue associated with intensive training. 2. It helps in the retention of muscular protein. 3. It heightens mental alertness thus helping to offset mental fatigue. With any amino acid supplement overdosing can lead to weakness and nausea so care should be taken in applying small doses and increasing them gradually until an optimum level is reached. Bear in mind that many protein powders and other supplements are fortified with amino acids so check the labels carefully. The manufacturer's instructions should be followed in all instances. Richard Mitchell is the creator of the bodybuildingadvisor.com website that provides guidance and information to athletes at all levels of bodybuilding experience. Go to Bodybuilding Advice to learn more about the issues covered in this article.
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Selection criteria are detailed on this web page:http://www.nlm.nih.gov/pubs/factsheets/jsel.htmlStep 2: Once on the PubMed web site, search for research articles using the generic (scientific) name of the supplement in question. Supplementmanufacturers must list the scientific name for their supplement's ingredients on thelabel and in advertisements. Supplements often contain many ingredients but usually only a few provide thepurported benefits. Those are the ingredients you want to evaluate--they are often the same ones the manufacturer highlights in advertisements.Step 3: This is the step some supplementcompanies don't want you to know. Before you click on the "Search" button at PubMed.org, limit your search to studies that utilize the right research methodology with the right population. The right research methodology is a randomized controlled trial (the double-blind, placebo control group design fits under this category) and the right population is human beings.Specifying human subjects is important because you want to know if the ingredients in a supplement have been shown to produce the advertised benefits in real live human beings--not just in rats pressing levers for food pellets or in a "case study" with one person. This is not to say that basic science research, which is often conducted initially with animals, is unimportant. On the contrary, such research usually serves as a crucial building block for subsequent clinicalresearch with humans. But basic science research does not provide scientific evidence for a supplement's beneficial health effects on human beings. Only research with human subjects, using randomized controlled trials, can offer such evidence. On the PubMed.org search page, click on the "Limits" tab located under the "Search" box. You will see a number of drop-down menus. First click on the Publication Type menu and then select Randomized Controlled Trial. Next click on the drop-down menu labeled, Humans or Animals and click on Humans.An ExampleMorinda citrifolia is the scientific name for a popular ingredient in a nutritional supplement. First search on PubMed for Morinda citrifolia, without placing Limits on your search. How many results did you receive? The count was 69 at the time I wrote this article. Looks impressive, huh? But now search for Morinda citrifolia after first placing Limits on the search as described above, so that you receive only those studies which provide more definitive scientific evidence for the positive effects ofMorinda citrifolia. How many journal articles did you find searching with the specified limits? I found 1. Thus, out of 69 articles found on PubMed.org, only one provides some evidence forMorinda citrifolia's beneficial effects. 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